Searchable abstracts of presentations at key conferences in endocrinology

ea0084op-13-66 | Oral Session 13: Basic 3 | ETA2022

Generation of human thyroid organoids from embryonic stem cells to rescue hypothyroidism

Romitti Mirian , Tourneur Adrien , Lasolle Helene , Detours Vincent , Singh Sumeet , Refetoff Samuel , Costagliola Sabine

Organoids are tiny, self-organized three-dimensional versions of an organ that are produced in vitro. Human organoids offer unique opportunities to model the development, physiology, and diseases of human tissues while complementing animal models and reducing the need for animal testing. In the thyroid field, there is a lack of a functional human in vitro thyroid model which allows to further explore various aspects related to thyroid development and disease....